Saturday, November 21, 2009

ESC and Skin

From Science Daily:
"For more than two decades, physicians have used cell culture techniques in order to obtain a sufficiently large area of skin to reconstruct the destroyed epidermis from a small sample harvested from the patients themselves."
So, we have existing solutions that work without ESC...
"Although this type of graft has been used with success, one of its limits is the time required (three weeks) to produce a sufficient amount of epidermis to cover the affected areas"
But we are impatient...
"the use of such grafts in animals with a weakened immune system to overcome potential graft rejection. Twelve weeks after transplantation, the mice presented localized areas of completely normal and functional adult human epidermis containing all the skin cell types"
Graft rejection? Oh yea, these are foreign cells, so the receiver will need to take immuno-suppressive drugs their whole life, or until they can receive a traditional graft.

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